Page 86 - RUFARS 2021 - Proceedings
P. 86

ISSN: 2659-2029
               Proceedings of the 4  Research Symposium of the Faculty of Allied Health Sciences
                             th
               University of Ruhuna, Galle, Sri Lanka
               August 26, 2021


               PP 26

                Prevalence of Risk Factors of Osteoporosis among a Group of Middle-aged
                                   Premenopausal Women in Sri Lanka

                                                                        3
                                     1#
                                                     2
                    Subasinghe H.W.A.S. , Lekamwasam S. , Ball P. , Morrissey H. , Waidyaratne E.I.
                                                            3
                                                                                        4
                     1 Department of Pharmacy, Faculty of Allied Health Sciences, University of Ruhuna
                          2 Department of Medicine, Faculty of Medicine, University of Ruhuna
                          3  School of Pharmacy, University of Wolverhampton, United Kingdom
                          4  Department of Anatomy, Faculty of Medicine, University of Ruhuna

                                   # Corresponding author: sewwandi_subasinghe@yahoo.com

               Background:  Osteoporosis  has  a  multitude  of  risk  factors  and  many  of  those  begin  in  the
               middle  age.  Early  recognition  and  management  of  risk  factors  in  the  middle  age  helps
               prevention of osteoporosis in old age.

               Objectives:  To  assess  the  prevalence  of  osteoporosis  risk  factors  among  a  group  of
               premenopausal women in Sri Lanka.

               Methods: This cross-sectional study included 323 community-dwelling premenopausal women
               aged  20-40  years.  Sociodemographic  data  and  the  prevalence  of  risk  factors  of  osteoporosis
               were  assessed  using  an  interviewer  administered  questionnaire.  Previous  history  of  fracture,
               parental  history  of  fragility  fracture,  prolonged  systemic  glucocorticoid  use  (>3  months),
               smoking and alcohol use, rheumatoid arthritis, chronic disease conditions, parity and duration of
               breast feeding, exposure to sunlight, calcium and vitamin D rich food intake were evaluated as
               main risk factors. Anthropometric measurements were made following standard procedures.

               Results: Mean±SD age and body weight of the study sample were 31±6 years and 54.5±12.0
               kg, respectively. Among the participants, 27.6% were overweight (BMI ≥25 kg/m ) and 20.1%
                                                                                  2
                                        2
               had  lower  BMI  (<18.5  kg/m ).  Approximately  13.7%  had  a  family  history  of  hip  or  major
               osteoporotic  fractures.  Prevalence  of  non-communicable  diseases  (diabetes,  hypertension,
               asthma, hypercholesterolemia) was very low (6%). None were current smokers or alcohol users
               or on prolonged glucocorticoid therapy. About 3.7% women did not consume any dairy product
               while one third of the sample had very low diary and non-dairy calcium rich food consumption.
               Median  (IQR)  duration  of  total  breastfeeding  was  48  (24−48)  months.  Among  the  breastfed
               women,  70%  had  very  longer  durations  of  breast  feeding  (>24months).  Daily  exposure  to
               sunlight was <2 hours in 55.7% of women.

               Conclusions:  Less  exposure  to  sunlight,  low  intake  of  calcium  rich  foods,  long-term  breast
               feeding and underweight are  the potentially  modifiable risk factors of osteoporosis prevalent
               among  middle  aged  premenopausal  women.  Lifestyle  modifications  are  the  best  option  to
               reduce them.

               Keywords: Osteoporosis, Risk factors, Women










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